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Andhela Leela Sairam

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Open access Sep 2026

Untargeted LC-MS-Based Metabolomics Reveals Metabolic Fate and Cellular Biochemical Disruptions Induced by 4,4-Diaminodiphenylmethane in Human Skin Fibroblasts.

Human exposure to 4,4'-diaminodiphenylmethane (MDA) occurs predominantly through dermal contact, yet its extra-hepatic biotransformation pathways and the metabolomic disturbances it induces remain poorly characterized. In this study, human skin fibroblasts were incubated with MDA, and untargeted LC-HRMS metabolomics wa...

Radhika Kawathe, Andhela Leela Sairam, Sridhar Chinthakindi · 0 citations

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