Andrea Becchetti

Orexins and neuregulins as exemplars of peptide physiology in the brain: experimental challenges and implications for neuropathology.

Neuropeptides and neurotrophic factors exert overlapping roles on synaptic maturation and plasticity. Although the relative intracellular signals are mostly elucidated, difficulties are met in discerning the dynamics of their extracellular action in vivo, which is largely determined by their peptide nature. We discuss...