Open access
Oct 2026
Effects of Spermidine Supplementation on Vascular Brain Health in Older Individuals with Subjective Cognitive Decline - An Exploratory MRI Analysis.
Spermidine supplementation benefits brain health and function in animal models, with emerging evidence suggesting cognitive benefits in humans. However, effects on human brain health remain unclear. In this randomized, double-blind, placebo-controlled trial (SmartAge), we investigated 12-month spermidine supplementatio...
C. Schwarz, Katharina Wurdack, S. Hetzer et al.
· Aging and Disease · 0 citations