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Author

Andrea Matamoros

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Oct 2026

The secretome of UC-MSC reprogrammed to a glycolytic metabolism promotes Treg generation and naive CD4 T cells stability in PBMC from rheumatoid arthritis patients.

OBJECTIVE Rheumatoid arthritis (RA) is characterized by persistent inflammation and dysregulated T cell responses. Mesenchymal stromal cells (MSCs) have immunomodulatory properties, but their clinical efficacy remains variable. We investigated whether metabolic reprogramming of umbilical cord-derived MSCs (UC-MSCs) tow...

N. Luque-Campos, C. Pradenas, E. Lara-Barba et al. · 0 citations
Open access Oct 2026

Resistance training prevents the development of sarcopenia induced by chronic cholestatic liver disease

Sarcopenia secondary to chronic cholestatic liver disease (CCLD) is linked to activation of the ubiquitin-proteasome system (UPS) and autophagy-lysosome system (ALS), impaired mitochondrial dynamics, and diminished mTOR signaling. Resistance training (RT) has shown benefits against age-related sarcopenia, but its effec...

Claudio Cabello-Verrugio, M. Valero-Breton, Franco Tacchi et al. · 0 citations

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