Background Pavlovian-to-instrumental transfer (PIT) paradigms assess how environmental cues influence instrumental behaviour. Our previous research linked PIT to alcohol use disorder (AUD) and high-risk drinking using monetary rewards during learning. To better capture alcohol-related cue effects, we developed a PIT pa...
Hao Chen, Christian Bäuchl, L. Thill et al.· bioRxiv· 0 citations
Pavlovian conditioned stimuli can compromise goal-directed behavior, particularly when they conflict with the required instrumental response. Previous research linked an increased impact of such Pavlovian-to-instrumental transfer (PIT) interference to risky drinking and alcohol dependence. However, it remained unclear...
L. Thill, Hao Chen, Christian Bäuchl et al.· bioRxiv· 0 citations
Background Deficits in inhibitory control are considered a central feature of alcohol use disorder (AUD), yet behavioral and neuroimaging findings have been inconsistent. One potential explanation is the marked heterogeneity of AUD, which encompasses multiple symptom dimensions that may differ in their underlying neuro...
J. Böhmer, Pablo Reinhardt, Marco Bottino et al.· bioRxiv· 0 citations
This study evaluated the latent structure and conceptual validity of the Research Domain Criteria (RDoC), General Health, and Clinical/Psychosocial clusters of the German Center for Mental Health (DZPG) Minimum Data Set (MDS). It aimed to determine whether these clusters represent interpretable constructs and demonstra...
Bernd R. Förstner, S. Böttger, Timm Seegert et al.· European Archives of Psychia...· 0 citations
It is found that smartphone-based, gamified tasks show promise to identify periods of heightened risk paving the way for mechanism-based, real-time interventions in AUD: specific decision-making alterations precede changes in consumption.
Hilmar Zech, Maria Waltmann, D. Reichert et al.· Biological Psychiatry: Cogni...· 0 citations
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