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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Andreas Martin

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Open access Sep 2026

Proteasomal surveillance of exposed cysteines

Cysteine residues are critical for both the catalytic activity and structural stability of many proteins, yet their high chemical reactivity threatens proteome integrity. Whether cells have specialized mechanisms to recognize and eliminate proteins with aberrant or exposed cysteines is unknown. By systematically analyz...

Elijah L. Mena, Ken C. Dong, Anthony Kairouz et al. · 0 citations
Open access Jul 2026

Identifying endogenous substrates of the 26S proteasome through site-specific photocrosslinking

Genetic code expansion is used to introduce a photo-crosslinkable unnatural amino acid into the yeast 26S proteasome and capture cellular protein substrates as they translocate through the proteasomal ATPase motor, representing an exciting avenue for probing the landscape of proteasomal substrates and its changes in re...

S. Restrepo, Andreas Martin · 0 citations

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