Author

Andrew E.-Y. Chuang

3 papers indexed here

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Review Aug 2026

Thymosin α-1 in Cancer Therapy: Immunomodulatory Mechanisms, Clinical Applications, and Translational Perspectives.

The biological functions, immunoregulatory mechanisms, and therapeutic potential of Tα1 in oncology are summarized to provide an updated perspective on the role of Tα1 as a potential adjunctive immunomodulatory agent in modern cancer immunotherapy.

Sih-Chi Chuang, Pei-Chia Hung, Lekshmi Rethi et al. · European Journal of Pharmaco... · 0 citations

Open access Sep 2026

A CD44-targeted PDA/ZnO redox-active nanocomposite that couples chemotherapy with mitochondrial stress and tumor immune remodeling

Bladder cancer therapy is frequently limited by inefficient drug retention and adaptive immune resistance within a hypoxic tumor microenvironment. Here, we report a CD44-targeted, fully synthetic nanocomposite (HPPZC) that converts chemotherapy into a mitochondria-associated therapeutic strategy accompanied by tumor im...

Andrew E.-Y. Chuang, Szu-Yu Tung, Kai-Yi Tzou et al. · Journal of Nanobiotechnology · 0 citations

Open access Jul 2026

HOF‐Stabilized Apple EV Nanocargo in an NIR‐Responsive Hydrogel Enables On‐Demand Therapeutic Modulation for Transdermal Deep‐Joint Osteoarthritis Therapy

Osteoarthritis (OA) is driven by intertwined pathological processes, including chronic inflammation, oxidative stress, immune imbalance, hypoxia, and aberrant angiogenesis, while current noninvasive therapies remain limited by insufficient deep‐joint delivery and poor multidimensional regulation. Here, an extracellular...

Yu-Wen Tseng, Pei-Wei Weng, Hsien-Tsung Lu et al. · Advanced Healthcare Material... · 0 citations