Open access
Oct 2026
Molecular mechanism of KRAS binding to BRAF and its regulation by the BRAF-specific region
Although the RBD engages KRAS through a conserved mechanism, the BRAF(CRD) adopts a hinge-like displacement away from KRAS, forming fewer contacts and contributing less to binding than CRAF(CRD).
D. Bonsor, Suzanne I. Sandin Lawrence, Timothy H. Tran et al.
· Structure · 0 citations