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Author

Andrew G. Yee

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2 papers indexed here

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Open access Sep 2026

The impact of α-synuclein overexpression on nigrostriatal transmission

Accumulation of wild-type α-synuclein in dopamine neurons of the Substantia Nigra pars compacta (SNc) is a pathological hallmark of Parkinson’s disease (PD), which commonly precedes neurodegeneration. Yet how α-synuclein accumulation affects nigrostriatal neurotransmission early in the progression of PD remains poorly...

N. Bergum, Andrew G. Yee, Robert H. Edwards et al. · 0 citations
Open access Jul 2026

Distinct forms of dopamine transmission control locomotion and learning

The neuromodulator dopamine is essential for voluntary movement and learning from experience. While these behaviors often occur simultaneously and rely on overlapping nigrostriatal dopamine circuits, they are also separable and can manifest independently. How a single neuromodulatory system controls such disparate aspe...

Matthew M McGregor, Andrew G. Yee, Selin Ekici et al. · 0 citations

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