Aug 2026
Tumor-tropic E. coli engineered as living T and NK cell engagers
Shao-Bo Yang, Anna Clara Bader, S. Sendker et al.
· bioRxiv · 0 citations
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Sep 2026
Cancers modulate processing and presentation of p53 neoantigens to evade T cell detection.
TP53 mutations occur early in malignant transformation as truncal events in tumor evolution and are therefore generally present in all descendant tumor cells, creating an immunological vulnerability. Here, we examined the immunogenicity and antigenicity of p53 neoantigens emerging from these truncal mutations. Comprehe...
Koji Haratani, Bruce R. Reinhold, J. Duke-Cohan et al.
· Immunity · 0 citations