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Andrew J. Schwab

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Open access Jan 2026

Serum Metabolomic Profiling Reveals Potential Mechanisms and Biomarkers of Seladelpar Treatment in Patients With Primary Biliary Cholangitis

Background Seladelpar, a potent and selective peroxisome proliferator‐activated receptor‐δ (PPARδ) agonist, is an approved second‐line therapy for primary biliary cholangitis (PBC) in patients with an inadequate response or intolerance to ursodeoxycholic acid (UDCA). In clinical studies, seladelpar significantly improv...

Yun-Jung Choi, Andrew J. Schwab, James Lim et al. · 0 citations

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