Proximity-ligation metagenomics reveals differential plasmid and chromosomal antimicrobial resistance gene carriage in disrupted gut ecosystems
Summary Distinct ecological pressures shape accumulation of antimicrobial resistance genes (ARGs) and virulence genes in the gut microbiome. In this study, we used proximity ligation shotgun metagenomics to characterize bacterial host-mobilome relationships associated with antimicrobial resistance and virulence genes i...