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A. Wilson

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Open access Jul 2026

Proteome-wide target profiling of α-helix mimetics

This represents the first direct cross-comparison of different helix mimetic scaffolds, revealing significant differences in proteome-wide selectivity.

Amrita Date, Archie Wall, Hannah Kiely-Collins et al. · 0 citations
Open access Jul 2026

Expanding all-α-helical protein space through rational computational design

De novo protein design is advancing rapidly1,2. This is being driven by AI to generate protein backbones, sequences, and structural models3–7. As a result, de novo designed proteins are becoming larger and more complex8–10, and increasingly explore new protein structures11,12. By contrast, natural proteins have evolved...

K. I. Albanese, Joel J. Chubb, L. Gutierrez-Rus et al. · 0 citations

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