Deletion of 12/15-Lipoxygenase Preserves Retinal Thickness and Function and Selectively Restores Dysregulated miRNAs in Experimental Diabetes Mice
Diabetic retinopathy (DR) remains a leading cause of blindness, characterized by progressive neurovascular dysfunction. While the enzyme 12/15-lipoxygenase (12/15-LO) and its metabolites are upregulated in DR, their interactions with epigenetic regulators, such as miRNAs, are poorly understood. This study investigates...