HIV-1 lentivirus with VSV-G envelope: Complex N glycosylation governs shifts in aggregation and infectivity state at close to physiological pH, serum, and Ca2+ levels
The goal of the study is to determine if the N-glycosylation on a virus affects its diffusion or solution state in different environmental conditions, and if the nature of the solution states has any consequence for the virus infectivity. HIV-1 lentivirus is frequently pseudo-typed with the envelope protein of Vesicula...