Open access
Jul 2026
Optimizing T Cell Priming Using TLR4/9 Combination Adjuvant For Robust Cell-Mediated Immunity Against Influenza 2307646
This work investigates the potential of IVAX-1, a combination of TLR4 (MPLA) and TLR9 (CpG 1018) agonists formulated in a squalene oil-in-water emulsion, to mediate protection and generate CMI and demonstrates the potential of TLR agonist combinations to elicit durable T-cell immunity.
Dan Nguyen, D. Davies, J. Felgner et al.
· Journal of Immunology · 0 citations