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Author

Ângela Gonçalves

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Oct 2026

Meso-scale spatial analysis of papilloma formation and clonal expansion in cancerized skin.

Somatic driver mutations pervade phenotypically normal epithelia, yet only a minority of clones progress to tumors. To understand how tissue context modulates clonal selection, we apply the classical two-stage DMBA/TPA model of carcinogenesis to mouse back skin. We collect coordinate-registered, meso-scale grids spanni...

V. Busa, Mikaela Behm, Pablo Baeza-Centurión et al. · 0 citations

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