Deletion of Pleiotrophin protects against high-fat diet-induced liver metabolic disease, independently of the sexual dimorphism in dietary response
Obesity is a global health problem linked to the development of metabolic syndrome and comorbidities such as metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH). Pleiotrophin (PTN) is a cytokine known for its role in tissue regeneration and energy...