Plpp3 regulates craniofacial morphogenesis but is dispensable for establishing the midbrain-hindbrain boundary
Phospholipid Phosphatase 3 (PLPP3), an integral membrane enzyme, is essential for embryonic development. It plays a critical role in lipid metabolism and in regulating the cell signaling of several bioactive lipid mediators. One of these lipids, LPA, has been suggested to participate in establishing the midbrain-hindbr...