Open access
Sep 2026
A context-dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma.
Acquired resistance to vemurafenib, a BRAFV600E-targeted therapy, remains a major challenge in melanoma. The translation initiation factor eIF6 has been implicated in cancer; however, its role in vemurafenib resistance is poorly understood. We investigated eIF6 using melanoma cell lines with distinct mutational backgro...
G. Kyriakopoulos, Antonia Petropoulou, A. Anastogianni et al.
· FEBS Letters · 0 citations