DIFFERENTIAL ACTIVATION OF G-PROTEIN SUBTYPES BY DOPAMINE D1 RECEPTOR ALLOSTERIC MODULATION
Allosteric modulation of G protein-coupled receptors (GPCR) is a rapidly advancing area of drug discovery with considerable therapeutic potential. In this study, we used various bioluminescence resonance energy transfer (BRET) assay configurations to investigate the differential activity of LY3154207, a dopamine D1 rec...