Aug 2026
High-Throughput On-Chip Screening Enables Rapid Adaptation of DNA Aptamers to SARS-CoV-2 Evolution.
A high-throughput aptamer engineering platform that combines a random-rational hybrid library diversification with repurposed MiSeq screening to rapidly reprogram aptamers against emerging SARS-CoV-2 spike variants is demonstrated, demonstrating a rapid and sequence-resolved aptamer engineering platform for adapting ap...
Yu-Jie He, Zhenglin Yang, Yu-An Kuo et al.
· ACS Nano · 0 citations