Sep 2026
β-Sheet Antimicrobial and Antimycobacterial Peptides with a High Therapeutic Index by Employing the Repeats of a 5-Mer Segment of α-Helical Cytolytic Melittin.
MLT-2 and MLT-3 showed appreciable in vivo efficacy against Escherichia coli American Type Culture Collection 25922-infection in mice in the intravenous route and inhibited transcription/translation in in vitro assays suggesting their intracellular mode of action.
R. Verma, Sariyah Akhtar, Jyotshana Saroj et al.
· Journal of Medicinal Chemist... · 0 citations