Aug 2026
Leishmania inhibits NLRP3 expression through IL-33/ST2 signaling driven SOCS1-mediated p65 degradation.
The dynamic interplay between pro- and anti-inflammatory cytokines plays a crucial role in regulating host immune responses. In our earlier study, we showed that Leishmania donovani-induced IL-33 destabilizes host cytokine dynamics by downregulating TNF-α and IL-12 and ensures intramacrophage parasite survival. Another...
Souravi Roy, Mayumi Mandal, Madhurima Banerjee et al.
· Journal of Immunology · 0 citations