Aniruddh Goteti

Prediction-Guided Design of a More Developable FGF21 Construct

For structural-biology and protein-production pipelines, the hardest part of a difficult protein is not the biology — it is obtaining a well-behaved sample for functional studies. Programs routinely stall at construct design, expression, and purification: deciding where to truncate, which tags to use, how to express, a...