Author

Anjali Saqi

2 papers indexed here

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Open access Sep 2026

Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis

Tumor progression is driven by dynamic interactions between cancer cells and their surrounding microenvironment. Here we integrate high-resolution spatial transcriptomics and evolving lineage-tracing technologies to elucidate how tumor expansion, plasticity and metastasis co-evolve with microenvironmental remodeling in...

Matthew G. Jones, Da-Wei Sun, Kyung Hoi (Joseph) Min et al. · Nature Genetics · 0 citations

Open access Aug 2026

A novel CAF population coordinates hyper-suppressive regulatory T cell recruitment and localization in lung cancer

Across many solid tumor types, cancer-associated fibroblasts (CAFs) are abundant and heterogeneous, with distinct subpopulations exerting immunomodulatory functions. Here we identify a novel population of immunomodulatory CAFs (imCAFs) in primary lung adenocarcinoma and pulmonary metastases, characterized by cell adhes...

Olivia R. Ringham, Monica Rivera, Lucas F. Loffredo et al. · Nature Immunology · 1 citation