Design, Molecular Docking and Neuroprotective Screening of Novel Pyrimidine-Based Acetylcholinesterase Inhibitors
Alzheimer's disease (AD) remains a multifactorial neurodegenerative disorder and currently there are only a few symptomatic therapies available to treat the cholinergic system. The pyrimidine scaffold has become a privileged scaffold for the design of multi-target directed ligands (MTDLs) that are effective at targetin...