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Author

Anna Fracassi

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Open access Jul 2026

Pharmacological modulation of p75 neurotrophin receptor in microglial cells improves resilience to rotenone cytotoxicity

The findings demonstrate that pharmacological modulation of p75NTR by LM11A-31 protects microglial cells against Rot-induced cytotoxicity and inflammatory activation, and may represent a promising therapeutic strategy to counteract microglial dysfunction and neuroinflammatory processes associated with Parkinson’s disea...

Alessio Valenza, D. Pensabene, Francesca Rendina et al. · 1 citation

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