Open access
Aug 2026
CRISPR-activation reveals key resistance genes and vulnerabilities of copy number variants in Candida albicans
Additive fitness effects of individual gene overexpression are a significant predictor of the fitness of multiple isolates with CNVs and can explain fitness trade-offs observed between classes of antifungal drug for the CNV isolates.
Pétra L. Vande Zande, Nicholas C. Gervais, Erika Schell et al.
· bioRxiv · 0 citations