Streptococcus agalactiae pigment toxin induces a rapid non-canonical cell death in human dendritic cells
Streptococcus agalactiae (Group B Streptococcus, GBS) is a major cause of neonatal sepsis and is increasingly associated with invasive infections in non-pregnant adults. GBS produces a cell wall-associated lipid toxin, the pigment (granadaene), a key virulence factor with cytotoxic and immunomodulatory properties. Whil...