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Author

Anna Schwager

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Review Oct 2026

Advances in modeling chromosomal aberrations to recapitulate genomic rearrangements.

Chromosomal aberrations, including aneuploidies and structural rearrangements, are key drivers of cancer and numerous genetic disorders. Experimental modeling of these alterations is essential for understanding their role in disease initiation and progression. Historically, chromosome engineering relied on methods that...

Victoria Ginestet, Anna Schwager, Y. Vassetzky et al. · 0 citations
Open access Aug 2026

Simultaneous single-cell profiling of chromatin, transcriptome and surface markers with OneCell CUT&Tag captures epigenomic reprogramming.

This approach uncovers epigenomic priming of basal cells in the mammary gland and captures the dynamics of basal-to-luminal transdifferentiation, suggesting that epigenomic and transcriptional remodeling do not occur in complete synchrony during cell-fate conversion.

Anna Schwager, Eve Moutaux, Adeline Durand et al. · 0 citations

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