RNA localization adds a fundamental layer to gene expression by determining when and where translation-ready mRNAs become available, yet how this timing is coordinated with nuclear architecture and cell-cycle progression remains unclear. Here we identify a subnuclear RNA niche at the nuclear speckle periphery that coup...
Josep Biayna, A. Baranovskii, Anusha Chaudhuri et al.· Nature Cell Biology· 0 citations
The state of the art in RNA structure prediction is reviewed, covering key training datasets, community benchmarks, and the performance of current models, as well as perspectives on integrating other data modalities, such as chemical probing signals and RNA modifications, as well as the emerging role of generative mode...
Lambert Moyon, Annalisa Marsico· Current Opinion in Structura...· 0 citations
Parnet is a multi-task foundation model trained end-to-end on 223 eCLIP-seq experiments spanning 150 RBPs to predict base-resolution RBP binding profiles directly from RNA sequence, and establishes the RBP interactome as a compact, functionally sufficient, and interpretable basis for foundation model pretraining in RNA...
