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Author

Annika Ladwig

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Open access Aug 2026

Granule microenvironment regulates the dual functions of FMR1

It is shown that the condensation propensity of FMR1 containing granules regulates the two antagonistic functions, such that phase separation by FMR1-CTD creates the molecular microenvironment necessary for the repressive activity, whereas reduction in phase separation is associated with increased translation.

Vaishali Grewal, Frank Wippich, Danilo Lüdke et al. · 0 citations

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