Anoop Viswan Koothattu

Protein Language Models and Graph-Based Reranking for Toxin-Binder Screening in Antivenom Discovery

Identifying proteins that neutralize snake venom toxins is a critical bottleneck in antivenom development, constrained by the scarcity of experimentally resolved toxin-binder structures and the high cost of wet-lab screening. This paper presents a computational screening pipeline that prioritizes toxinbinder candidates...