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Anoushka Sinha

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Review 2026

From Double-Strand Breaks to Precision Edits: A Comparative Review of Modern Genome Editing Tools

This review compares Cas9-mediated homology-directed repair (HDR) with generations of cytosine base editors (CBE1–CBE3), adenine base editors (ABE1-ABE7), and prime editors (PE1–PE3b), focusing on their mechanistic distinctions, efficiencies, delivery challenges, and therapeutic applications.

Anoushka Sinha · 0 citations