Review
Open access
Aug 2026
PKC isoforms in hematopoietic lineages and myeloid/lymphoid leukemias: mechanistic insights and therapeutic prospects
Leukemia remains a major clinical challenge due to high rates of drug resistance and recurrence, necessitating the identification of novel therapeutic targets. Protein kinase C (PKC) family, a central signaling hub regulating cell proliferation, differentiation, and apoptosis, has been implicated in hematological malig...
Xu Wang, Chun-Ming Wang, Suling Li et al.
· Frontiers in Oncology · 0 citations