Open access
Aug 2026
Multi◻region whole◻genome and transcriptomic profiling uncovers plastic, subclone◻linked cell states in high◻grade diffuse astrocytomas
A framework for understanding how early-established genomic backbones and regional transcriptional plasticity jointly drive phenotypic diversity is provided for understanding how genomic diversification intersects with transcriptional plasticity remains incompletely understood.
Serafiina Ohlsbom, S. Mäntylä, R. Nätkin et al.
· bioRxiv · 0 citations