Poly(I:C) suppresses NF1-associated optic pathway glioma growth through TLR3-dependent and TLR3-independent modulation of microglial ERK signaling
Immunomodulatory therapies have emerged as promising treatments for cancer, where poly(I:C), a synthetic double-stranded RNA, is currently under clinical investigation for its ability to control myeloid cell function and T cell infiltration. While poly(I:C) mimics viral infection and activates Toll-like receptor 3...