Influenza A virus H5Nx genotypes assigned by genetic similarity are incongruent with global phylogenies
Influenza A virus H5N1 and related subtypes (H5Nx) have broad host ranges and pose a pandemic risk. Since early 2022, H5 clade 2.3.4.4b has predominated globally, causing unprecedented mortality in wild birds, poultry, and mammals, with spillovers to humans. Accurate viral classification is essential for tracking H5Nx...