Open access
Sep 2026
Selective vulnerability and resilience of thalamic neuronal populations in Frontotemporal Dementia
Abstract Frontotemporal dementia (FTD) caused by progranulin (GRN) mutations is associated with pronounced thalamic degeneration, yet the cellular basis of selective thalamic vulnerability remains poorly understood. Here, we generated an integrated single-nucleus RNA-sequencing atlas of the human antero-median thalamus...
Amber E. Trujillo, Mira Sohn, Magdalena J. Macias et al.
· Research Square · 0 citations