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Author

Antonio Díaz

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Open access Oct 2026

Decline of chaperone-mediated autophagy in aging impairs macrophage clearance of senescent cells.

Autophagy dysfunction and senescence are established drivers of aging, but their potential interaction remains poorly understood. Here we show that age-related decline of chaperone-mediated autophagy (CMA), a pathway for selective lysosomal protein degradation, changes senescent cell properties and impairs their immune...

Rebecca Sereda, Kristen Lindenau, Antonio Díaz et al. · 1 citation

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