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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Anupam Bandyopadhyay

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Review Oct 2026

Beyond Antibodies: Glypican-3-Targeting Peptides for Precision Hepatocellular Carcinoma Theranostics.

Glypican-3 (GPC-3) is a cell-surface glycoprotein, highly expressed in hepatocellular carcinoma (HCC) but largely absent in normal adult liver tissues, making it a clinically compelling biomarker and therapeutic target. Although monoclonal antibodies and antibody-drug conjugates have proven to be GPC-3-targeted therapi...

Narendra R. Nagpure, N. M. Tripathi, Neelam Verma et al. · 0 citations
Open access Sep 2026

Conformationally restrained de novo peptides to modulate Skp1-Skp2 interaction of the SCF E3 ligase.

De novo peptide sequences are introduced through in silico screening of a peptide pool to target the Skp1-Skp2 core interface and establish the potential of first-in-class peptides in targeting the Skp1-Skp2 interface for the treatment of cancers driven by Skp2.

Simran Tolani, N. M. Tripathi, H. Antil et al. · 1 citation

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