Author

Anwar M. Alnakhli

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Open access Oct 2026

The Impact of an Intensive Care Unit Antimicrobial Stewardship Program on the Appropriateness of Meropenem Prescribing at a Tertiary Hospital: A Retrospective Quasi-Experimental Study

Background: Carbapenem-resistant Enterobacteriaceae (CRE) prevalence has been increasing in Saudi Arabia, posing a significant public health concern. Antimicrobial stewardship programs (ASPs) play an important role in reducing resistance by ensuring appropriate antibiotic use. Our study aimed to assess the appropriaten...

L. I. Alnajjar, Taif A. Alahmari, Shahad A. Almutairi et al. · Antibiotics · 0 citations

Sep 2026

Cardioprotective role of vincamine in cyclophosphamide-induced cardiotoxicity through modulation of AMPK/SIRT1, PI3K/Akt, and MAPK pathways.

VIN attenuated changes in the AMPK/SIRT1 and PI3K/Akt axes, MAPK, TLR4/NF-κB p65 signaling, as well as NLRP3-related signaling in a dose-responsive manner, and its cardioprotective effects were accompanied by improved redox balance, increased AMPK/SIRT1 and PI3K/Akt expression, reduced phosphorylated MAPK abundance, an...

Mohammed Tarek Seddek, A. Awad, Marwa E. Elsherbiny et al. · Naunyn-Schmiedeberg's Archiv... · 0 citations