Author

Aparna Saripella

3 papers indexed here

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Open access Oct 2026

Difficulty climbing stairs or walking one block on the FRAIL scale is associated with adverse postoperative outcomes in older surgical patients.

BACKGROUND Frail individuals represent a high-risk group for postoperative complications. The FRAIL (Fatigue, Resistance, Ambulation, Illnesses, and Weight Loss) scale is a self-reported tool for assessing frailty. While prior studies have linked overall FRAIL scores with adverse outcomes, the association of individual...

Tony Tan, Ellene Yan, Yasmin Alhamdah et al. · Journal of clinical anesthes... · 0 citations

Review Open access Sep 2026

Efficacy and safety of preoperative intranasal dexmedetomidine in adults: a systematic review and meta-analysis of randomized controlled trials

Background: Airway manipulation during General Anesthesia (GA) can produce sympathetic activation and hemodynamic instability. Intravenous (IV) dexmedetomidine attenuates these responses but may cause bradycardia or hypotension. Intranasal (IN) administration is a noninvasive alternative with uncertain evidence in adul...

V. Voznyy, Mouad Elganga, Leya Tawfik et al. · Brazilian Journal of Anesthe... · 0 citations

Open access Sep 2026

Cognitive impairment influences perioperative quality of life in older surgical patients: A multicenter longitudinal study.

BACKGROUND The impact of cognitive impairment (CI) on perioperative quality of life (QoL) in older surgical patients remains under-explored. We compared longitudinal QoL trajectories by CI status and examined associations between preoperative QoL and postoperative outcomes. METHODS Patients aged ≥65 years undergoing...

Ellene Yan, Jessica Xiong, Monica Yuen et al. · Journal of clinical anesthes... · 0 citations