Open access
Aug 2026
TBC1D23-AAVR interaction drives endosome-to-TGN trafficking required for rAAV transduction.
TBC1D23 is defined as a receptor-proximal trafficking module that couples AAV-AAVR engagement to vesicle transport, revealing a missing core regulatory step in AAV retrograde transport that is essential for productive rAAV transduction.
Xiujuan Zhang, Ariful Habib, Shane McFarlin et al.
· Proceedings of the National... · 0 citations