Linker histone H1 is an essential chromatin architectural protein that compacts chromatin into transcriptionally silent regions by interacting with nucleosomal and linker DNA while rapidly exchanging in vivo. How H1 targets nucleosomes while being dynamic remains unanswered. Using a single-molecule strategy, we investi...
E. Akbari, Nathaniel L. Burge, M. Valdimarsson et al.· Molecules and Cells· 0 citations
Single-molecule spectroscopy is emerging as a powerful approach for elucidating the molecular structure and dynamics of biomolecular condensates. Unlike ensemble methods, it can resolve heterogeneous conformations, dynamics, interactions, concentrations, and transport properties across a broad range of length- and time...
Benjamin Schuler, Aritra Chowdhury, Miloš T. Ivanović et al.· Current Opinion in Structura...· 0 citations
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