MOLECULAR MECHANISMS OF CYTOKINE-INDUCED CARTILAGE DESTRUCTION IN RHEUMATOID ARTHRITIS
Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes long-term destruction of cartilage and leads to irreversible arthritis. Pro-inflammatory messengers such as interleukin-1 beta (IL-1 beta), tumour necrosis factor-alpha (TNF alpha), interleukin-6 (IL-6), and interleukin-17 (IL-17)—drive this destruct...