Arman Namdari-Miraaghaie

Overcoming outer membrane barrier in gram-negative bacteria by PCNP-PVP-SE1 phage endolysin: Evidence from molecular docking, molecular dynamics and experimental analyses.

The increasing prevalence of antimicrobial resistance among Gram-negative pathogens necessitates the development of alternative antibacterial strategies. Bacteriophage-derived endolysins represent a promising class of antimicrobials; however, their limited ability to traverse the outer membrane of Gram-negative bacteri...