Review
Open access
Oct 2026
The PI3K/AKT/mTOR Pathway Is a Major Intracellular Regulator of Mast Cells Implicated in the Gut–Brain Axis and Mediates Inflammation
It is demonstrated that the PI3K/AKT/mTOR pathway is a central hub linking MC activity, inflammation, and gut–brain communication, and the potential clinical applications of this knowledge are discussed.
P. Conti, F. Mastrangelo, Armando Coppola et al.
· Gastrointestinal Disorders · 0 citations