Encapsulation of Annona muricata Acetogenins in Self-Nanoemulsifying Drug Delivery Systems (SNEDDSs): Controlled Release and Antiproliferative Activity in MC-38 Colon Cancer Cells
Acetogenins (ACGs) are bioactive compounds typically found in the Annonaceae family, such as soursop (Annona muricata), and have demonstrated strong antineoplastic effects at very low doses across different cancer cell lines. However, their poor water solubility limits their bioavailability and bioactivity. This resear...